Effects of RU 486 on the Early Luteal Function in Pseudopregnant Rats

Title

偽妊娠ラットの初期黄体機能に対するRU486の影響

Creators Kawamoto Kazunori

Source Identifiers

Creator Keywords

ラット偽妊娠黄体昨日プロゲステロン RU486

Effects of an anti-progesterone substance, RU 486, on the luteal function were studied in pseudopregnant rats. The 2mg/kg injection RU 486 between day 2 and 9 of pseudopregnancy could not affect on the ovarian function until day 8 (the ascending and the plateau phases) of pseudopregnancy, but did induce luteolysis on day 10 (the descending phase) of pseudopregnancy. On the other hand, the lOmg/kg injection of RU 486 rather induced ovulation, formed new corpora lutea resulted in the increase in serum progesterone levels on day 10 of pseudo- pregnancy. These results indicate that progesterone is an important factor to maintain the pseudopregnancy in rats.

Subjects

医学 ( Other)

Languages jpn

Resource Type journal article

Publishers 山口大学医学会

Date Issued 1992-12

File Version Not Applicable (or Unknown)

Access Rights metadata only access

Relations

[ISSN]0513-1731

[NCID]AN00243156

Schools 医学部