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Monoclonal antibody against human colonoc adenoma

山口医学 Volume 38 Issue 3 Page 215-219
published_at 1989-06
Title
ヒト大腸線腫に対するモノクローナル抗体の作製
Monoclonal antibody against human colonoc adenoma
Creators Miyahara Taeko
Creators Fujikura Yoshihisa
Creators Harima Takashi
Creators Yasutake Ryujiro
Creators Matsuura Shinjiro
Creators Yoshimura Syunji
Creators Fukumoto Tetsuo
Creators Takemoto Tadayoshi
Source Identifiers
We have generated weo monoclonal antibodies (UB-21, UB-22), which were produced by hybridoma cells, fusing mouse myeloma cells (NS-1) with the spleem cells of a BALB/c mouse that has been immunized with the suspended human colonic adenomas. Using an indirect immunofluorescence method, the presence of the anatigen against UB-21 and UB-22 was detected : it was detected in the normal human liver. UB-21 was detected in the large and small intestine of monkey, but UB-21 and UB-22 were negative with the intestine of the rat, rabbit raccoon, and badger. These findings suggested that these monoclonal antibodies (UB-21, UB-21) were specific for human and monkey's intestinal component and might be useful for analyzing normal and milignant human intesine.
Subjects
医学 ( Other)
Languages jpn
Resource Type journal article
Publishers 山口大学医学会
Date Issued 1989-06
File Version Not Applicable (or Unknown)
Access Rights metadata only access
Relations
[ISSN]0513-1731
[NCID]AN00243156
Schools 医学部