Effects of diazep (comelian) on aggressive behavior induced by clonidine

Clonidine によって生ずるマウスの攻撃行動に対するdilazep (comelian) の作用

Effects of diazep (comelian) on aggressive behavior induced by clonidine

Creators Ushijima Itsuko

Creators Kaneyuki Hiroshi

Creators Hara Takahide

Creators Kishimoto Osamu

Creators Soeda Koichiro

Creators Kudou Ryoji

Creators 堤 千種

Creators Mizuki Yasushi

Creators Yamada Michio

This study investigated the ability of dilazep (comelian) to prevent clonidine induced aggressive behavior in mice. Mice administered high doses of clonidine (20-50 mg/kg i.p.) exhibited aggressive behavior in dose dependent manner. Dilazep (5-20 mg/kg i.p.) dose-dependently inhibited the aggressive behavior induced by clonidine (50 mg/kg i.p.). Dilazep (2mg/kg i.p.), adenosine (10mg/kg i.p.), dipyridamole (10 mg/kg i.p.) or N^6-cyclohexyl adenosine (CHA

[ISSN]0513-1731

[NCID]AN00243156