Studies of Gastro-Mucosal Changes in the Patients with Chronic Liver Diseases

慢性肝疾患と胃十二指腸潰瘍性病変

Studies of Gastro-Mucosal Changes in the Patients with Chronic Liver Diseases

Creators 福本 陽平

Creators 前谷 昇

Creators 永富 裕二

Creators 沼 義則

Creators 安藤 啓次郎

Creators 坪田 若子

Creators 斉藤 満

Creators 小田 正隆

Creators 江崎 隆朗

Creators 竹内 憲

Creators 荻野 昌昭

Creators 弘 景子

Creators 半田 哲朗

Creators 小西 知己

Creators 飯田 洋三

Creators 児玉 隆浩

Creators 沖田 極

Creators 岡崎 幸紀

Creators 竹本 忠良

The relationship between chronic liver diseases and gastro-duodenal lesions was analized from the aspect of clinico-pathological changes in these organs. In the comparative study on the patients with chronic liver diseases and peptic ulcers, it was found that there was a positive correlation between these diseaes, and with advance of liver cirrhosis the incidence of peptic ulcer and erosion was increased. In order to evaluate causative factors of gastric ulcer and erosion in the patients with chronic liver diseases, the measurement of serum gastrin levels, gastric acid secretion and plasmin activity of gastric mucosa as well as the examination of the severity of esophageal varices, liver functions and morphology were performed. As the results, it was suspected that a lowered defence mechanism due to circulatory disturbance in the gastro-intestinal mucosa was an important causative factor in such a particular condition of liver diseases.

[ISSN]0513-1731

[NCID]AN00243156