Studies on the Antibiotics of Bacillus aneurinolyticus (2) Preliminary examination for extraction of the crude growth inhibitor and test of its physico-chemical feature

Bcillus aneurinolyticus の産生する抗生物質 第2報 Bcillus aneurinolyticusの産生する発育阻止物質抽出のための予備実験 (1) : 粗物質の生物化学的諸性状

Studies on the Antibiotics of Bacillus aneurinolyticus (2) Preliminary examination for extraction of the crude growth inhibitor and test of its physico-chemical feature

Creators Yoshii Zensaku

Creators Konishi Hisanori

Creators Kobayashi Syu

Creators Motoki Yoshinobu

Creators Takamura Akira

Growrh　inhibitor against candida was extracted crudely from the cultures of Bacillus aneurinolytics (BKA) and its physico-chemical features were examined. The results obtained are as follows : a) Heat-stability : Resistant at 120℃ for 15 minutes. b) Infuluence by inhibitors for thiaminase Ⅱ : No effect. c)　pH examination : Stable above, unstable below pH 6 . d) Salting out : Highest　at a 40% concentration of ammonium sultfate. e) Solubility in effective substance in the growth inhibitor of BKA was considered to be a kind of antibiotic. Also, the conditions for its preliminary were introduced.

[ISSN]0513-1731

[NCID]AN00243156