Intraoperative Radiation Therapy for Carcinoma of the Pancreas
The bulletin of the Yamaguchi Medical School Volume 38 Issue 3-4
Page 105-109
published_at 1991-12
Title
Intraoperative Radiation Therapy for Carcinoma of the Pancreas
Creators
Ebe Kazuyu
Creators
Nishikawa Eiichi
Creators
Suda Hiroki
Creators
Honma Yutaka
Creators
Kawamura Mitsutoshi
Creators
Okada Morihisa
Creators
Karino Yuichi
Creators
Nakada Taishi
Creators
Nakanishi Takashi
Creators
Uchiyama Tetsuzi
Creators
Hamanaka Yuichiro
Creators
Suzuki Takashi
Source Identifiers
Creator Keywords
Intraoperative radiation therapy (IOR)
Carcinoms
Pancreas
Intraarterial infusion
Radiosensitizer
RK28
Rabbit
VX2 tumor
Intraoperative radiation therapy (IOR) was performed on 13 patients with carcinoma of the pancreas. Seven cases were resectable and 6 cases wre unresectable. Tumor regression was observed in 5 of 6 unresectable tumors. Relief of abdominal pain was achieved in all 6 cases. The median survival of 13 patients was 145 dyas. Intraarterial infusion of hypoxic cell radiosensitizer RK28 was examined as a model of future clinical application for IOR using a rabbit VX2 tumor system. The tumor regression slopes were statistically different (P<0.01). But the difference in long-term survival was not statistically significant (P<0.10). Intraarterial infusion of RK28 is clinically promising in the future.
Languages
eng
Resource Type
departmental bulletin paper
Publishers
Yamaguchi University Graduate School of Medicine
Date Issued
1991-12
File Version
Version of Record
Access Rights
open access
Relations
[ISSN]0513-1812
[NCID]AA00594272
Schools
医学部