Age－dependent Variations in Chemiluminescence Response of Rat Whole Blood
The bulletin of the Yamaguchi Medical School Volume 35 Issue 1-2
Page 1-5
published_at 1988-06
Title
Age－dependent Variations in Chemiluminescence Response of Rat Whole Blood
Creators
Kimura Yoshiko
Creators
Mise Junichi
Creators
Fujikura Yoshihisa
Creators
Fukumoto Tetsuo
Source Identifiers
Creator Keywords
Polymorphonuclear leukocyte
Phagocytic function
Chemiluminescence
Rat
Aging
Chemiluminescence (CL), one of the assay system for phagocytic functions of leukocytes, especially of polymorphonuclear leukocytes was used for assessing the agerelated changes of immunocompetence in rat. The estimation of CL was carried out using freshly drawn unfractionated whole blood. The peak CL responses in newborns and relatively old rats were low compared to those in adult rats, although only the difference in the newborn group was statistically significant. The kineticproperties of CL response of newborns were also different from those of other age groups of rats. These resulta suggest the age-related changes of phagocytic functions may exist which may contribute to the high susceptibility to infection of old animals and newborns.
Languages
eng
Resource Type
departmental bulletin paper
Publishers
Yamaguchi University Graduate School of Medicine
Date Issued
1988-06
File Version
Version of Record
Access Rights
open access
Relations
[ISSN]0513-1812
[NCID]AA00594272
Schools
医学部