Cross-reactivity between sera from dogs experimentally infected with Dirofilaria immitis and crude extract of Toxocara canis
Korean journal of parasitology Volume 40 Issue 4
Page 195-198
published_at 2002-12
Title
Cross-reactivity between sera from dogs experimentally infected with Dirofilaria immitis and crude extract of Toxocara canis
Creators
Song Kun-Ho
Creators
Cho Kyu-Woan
Creators
Lee Sang-Eun
Creators
Kim Duck-Hwan
Creator Keywords
Dirofilaria immitis
cross-reactivity
ELISA
immunoblotting
Toxocara canis
This study was performed to investigate whethere there is cross-reactivity between Dirofilaria immitis and three intestinal nematodes of dogs. In ELISA, D. immitis-infected dog sera obtained at the 4th molting stage (9-11 weeks) and microfilaremic stage (25-30 weeks) were shown to be highly reactive with crude extract of T. canis. In immunoblotting, some antigenic fractions, 44, 57, 88, 100 kDa of crude extract of T. canis, were found to be positive reaction with sera of dogs infected with D. immitis. However, little or no cross-reaction were observed between sera of D. immitis-infected dogs and crude extract antigen of T. vulpis or A. caninum. These result suggest that there are partial cross reaction between sera of D. immitis-infected dogs and the antigen of T. canis.
Languages
eng
Resource Type
journal article
Publishers
Korean Society for Parasitology
Date Issued
2002-12
File Version
Version of Record
Access Rights
open access
Relations
[ISSN]0023-4001
[NCID]AA00712368
[isVersionOf]
[URI]http://www.parasitol.or.kr/kjp/index.php
Schools
農学部